Adipocyte metabolism
نویسندگان
چکیده
منابع مشابه
Adipocyte metabolism and obesity.
Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review how fuel partitioning between adipocytes and other tissues affects insulin signaling pathways. We discuss the role of adipose tissue inflammation in adipocyte metabolism and whole-body insulin sensitivity. Finally, we mention the role of adipokines in autocrine and paracrine signaling.
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For many years, adipose tissue was considered a passive tissue with the only function of storing excess energy as triglycerides and releasing fatty acids according to necessity. Now it becomes increasingly clear that adipose tissue is an endocrine organ that plays a critical role in modulating energy expenditure and homeostasis. White adipose tissue is thus responsible for the secretion of an a...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2002
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd902